C.H. Arrowsmith

University Health Network (CA)

Research Areas

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H-index

113

Publications

3095

Citations

43213

i10-index

394

Publications & Citations Over Time

Top Cited Publications

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Title	Year	Citations
Histone Recognition and Large-Scale Structural Ana...	2012	1742
Epigenetic protein families: a new frontier for dr...	2012	1304
Consistent blind protein structure generation from...	2008	864
The promise and peril of chemical probes	2015	847
Ductal pancreatic cancer modeling and drug screeni...	2015	746
Somatic mutations at EZH2 Y641 act dominantly thro...	2010	597
Chemical screening methods to identify ligands tha...	2006	593
Global analysis of protein folding using massively...	2017	556
Self-renewal as a therapeutic target in human colo...	2013	533
A chemical probe selectively inhibits G9a and GLP ...	2011	531

Publications

1.
Histone Recognition and Large-Scale Structural Analysis of the Human Bromodomain Family
Year: 2012Citations: 1742DOI: 10.1016/j.cell.2012.02.013
2.
Epigenetic protein families: a new frontier for drug discovery
Year: 2012Citations: 1304DOI: 10.1038/nrd3674
3.
Consistent blind protein structure generation from NMR chemical shift data
Year: 2008Citations: 864DOI: 10.1073/pnas.0800256105
4.
The promise and peril of chemical probes
Year: 2015Citations: 847DOI: 10.1038/nchembio.1867
5.
Ductal pancreatic cancer modeling and drug screening using human pluripotent stem cell– and patient-derived tumor organoids
Year: 2015Citations: 746DOI: 10.1038/nm.3973
6.
Somatic mutations at EZH2 Y641 act dominantly through a mechanism of selectively altered PRC2 catalytic activity, to increase H3K27 trimethylation
Year: 2010Citations: 597DOI: 10.1182/blood-2010-11-321208
7.
Chemical screening methods to identify ligands that promote protein stability, protein crystallization, and structure determination
Year: 2006Citations: 593DOI: 10.1073/pnas.0605224103
8.
Global analysis of protein folding using massively parallel design, synthesis, and testing
Year: 2017Citations: 556DOI: 10.1126/science.aan0693
9.
Self-renewal as a therapeutic target in human colorectal cancer
Year: 2013Citations: 533DOI: 10.1038/nm.3418
10.
A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells
Year: 2011Citations: 531DOI: 10.1038/nchembio.599

About C.H. Arrowsmith

C.H. Arrowsmith is a researcher with 3095 publications and 43213 citations. They are affiliated with University Health Network. Their research focuses on . With an h-index of 113, they are among the top researchers in their field.

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Distribution of citations across publications

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Impact Metrics Over Time

Citations per publication by year